According to Edmunds Inside Line, big changes are coming to large vans in the next few years. http://www.insideline.com/future-vehicles.html
Here's what we can look forward to, according to Edmunds.
Dodge: In the 2013 model year, Dodge will import Fiat's large van.
Ford: In 2014 model year, the Econoline will be replaced by the Transit, Ford's large European van
Mercedes: The Sprinter moved back to MBZ in 2010, and will continue to be sold.
Nissan: The Nissan commercial van is available this Summer as a 2011 model. The Nissan is designed with a pickup truck front end and a tall van body on the rear. It's not clear if this is a smart move by Nissan (van buyers are pretty traditional), or if their offering will seem dated compared to the slick new Ford, Dodge and Mercedes vans.
This leaves the Chevrolet Express as the last of the conventional American vans by 2014.
Will these platforms be as useful for ExPo-style travel as the current vans are? Will we ever see factory 4x4 setups on vans sold in USA? (for example, Mercedes makes a 4x4 version of the Sprinter, but it's not imported here)