MTB or road, the slight weight savings is far overshadowed by the difficulty of repairing a flat.
All you need to repair a flat with a tube tire is a patch.
both my MTB and road bike have a pack of patches, as well as a spare tube on board at all times. Funny though, I go through MANY more patches on my road bike. Even rolling on 120PSI 18mm tires :Wow1:
....but I never get flats, I ride 3 times a week on a good week, and I have damaged the side walls of a tubeless tire twice in the past 2 years. I repaired it both times with a spare tube, and one of those times I put a patch on the inside to keep the tube from popping out of the rift like bubble gum bubbles....it might not have been necessary, as the kevlar usually holds where rubber dose not.
But in the spring of 2008 (before I switched to tubeless) I got 3 flats in one short ride, I had to take the wheel off 4 times because one of my "patches" (trying to be dramatic about the word patches) didn't hold! I got eaten by mosquitos, the sun went down and i didn't bring a light, it was suppose to be a short ride! I've been tubeless ever since I wont go back, no way in hell would I deviate from my current set up of tubeless, spare tube, pump AND co2, and patch kit. I even keep a spare tire in the truck, a riding buddy or my self could retrieve it so the other person doesn't have to WALK off the trail (witch would be beneath me).
One time my riding buddy had a tubeless tire get a god awful pregnant spot on both sides, as it came apart at the seems and started rubbing the frame. He had a 26er so my spare tire wouldn't help, but luck would have it happen at the end of the trail and SOMEHOW didn't explode. I would chock that up to old tires rather than tube or no tube debate. I've also seen a tire with tube blow up out of no where! 30 psi, new bike, just finished a 12 mile trail, loaded in the truck when minutes later, BLAM! 6 inch rip out of the blue.
What I really am trying to say is crap can happen to any rig, but casual flats because of mesquite, cactus, briers, thorns, devil's walking stick, prickly ash, the dungy wucky bird, ect. are a thing of the past with tubeless and stans.