I know a little... The OM366LA is a 5.95lt straight 6 turbo diesel. They are a solid reliable engine, and were a replacement for the 5.6lt OM352 in the 1617's. Both are reasonably good on fuel, but both are under powered in any truck over 8 or 9 tonnes... The 1120 that was here is an 80kmh animal. Much more is a thrash. I drove 4x2 1617's, and 6x4 Mercedes 2421's which had a 10.9lt V6 OM401LA when I was in Africa... The V6 2421 had the edge on the straight 6 1617, but only just, and always sounded like someone rattling a tin with a few bolts in the bottom! Our 1222A has the later 10.9lt OM441LA V6 engine which is 220hp in naturally aspirated form, and jumps to 340hp in turbo intercooled form. It's quite smooth, and more refined than the original OM401. For a truck over 10 tonnes, the larger engines are a must. The smaller in line 6 will always be better on fuel, but I think the larger V6 and V8's are easier to work on.. With singular cylinder heads, fixing them on the side of the road is easier... We plan to carry a spare head and single piston gasket set... I recently found out about a much bigger 12lt OM501 V6 in the Actros. I know little about it, but its power ranges from 310hp to 480hp. Our truck is on the bigger side at 7.8m long, and being an all steel frame in the body, I'm guessing it'll be between 10 and 11 tonnes. I plan to utilise the turbo and intercooler of our donor truck taking our 220hp V6 up to around 300hp. My engine of choice would be an OM442 15.1 V8 twin turbo at around 350hp as its smooth, unstressed and sounds great... The fuel bill would be at least a 3rd more than the smaller 6's though, so I settled on the later V6, as it's not too big, and it's what I could find.
In a word, if you are going for an 'old school' truck under 9 tonnes, the straight 6 is the go. 9 tonnes or above look for a late V6, and 12 tonnes and above, find a V8! With a later Atego, Actros or similar, the common rail fly by wire engines are undoubtedly more efficient and quieter, but they don't like dirty fuel, and you need diagnostics equipment to fix them which is hard to find in third world countries.